Search results for "Ascorbyl Free Radical"

showing 1 items of 1 documents

Impact of high-fat diet on antioxidant status, vascular wall thickening and cardiac function in adult female LDLR<sup>–/–</sup> mice

2012

International audience; Background: Western diet, rich in saturated fatty acids and cholesterol, is associated with increased cardiovascular risk. We thus investigated in female mice the influence of this diet on plasma antioxidant status, vascular wall thickening and cardiac function. Methods and Results: Adult female C57BL/6J wild type (WT) and LDLR–/– mice were fed a normal diet (ND) or a high-fat diet (HFD) for 17 weeks. HFD induced an increase in plasma lipids and vitamin C (Vit C) levels in both groups but at a much higher level in LDLR–/– and a decrease in plasma ascorbyl free radical levels to Vit C ratio (an endogenous oxidative stress index) in LDLR–/–. We only found a slight decr…

Cardiac function curveAortic archmedicine.medical_specialtyAntioxidantOxygen radical absorbance capacityNormal dietAscorbyl Free Radicalmedicine.medical_treatment030204 cardiovascular system & hematologymedicine.disease_cause03 medical and health scienceschemistry.chemical_compound0302 clinical medicine[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemInternal medicinemedicine.arterymedicineVitamin C030304 developmental biologySystolic Function0303 health sciencesOxygen Radical Absorbance CapacityAortic ArchVitamin CCholesterolbusiness.industryOxidant/Antioxidant StatusHigh-Fat Dietfood and beveragesnutritional and metabolic diseases3. Good healthSurgeryEndocrinologychemistryEchocardiographylipids (amino acids peptides and proteins)businessOxidative stress
researchProduct